SNAP-8 20mg
Ships from USA
1–3 day delivery
Free Shipping
On orders $150+
Peptide Handling & Storage Guide
Storage temperature, shelf life & reconstitution (PDF)
99%+ Purity
COA included
Same-Day Shipping
Orders before 2PM EST
Secure Checkout
SSL encrypted
Shipment Protection
Lost or damaged — reshipped free
Compound Information
- Type
- Synthetic octapeptide (SNAP-25 fragment analog)
- Molecular Formula
- C41H70N16O16S
- Molecular Weight
- 1075.2 g/mol
- CAS Number
- 868844-74-0
- Purity
- 99%
- Sequence
- Ac-EEMQRRAD-NH2
- Also known as
- Acetyl octapeptide-3
Reference chemistry (free base) from public chemical databases and peer-reviewed literature. For laboratory research identification only.
Research Use Only. Not for human consumption. For laboratory and scientific research purposes only.
About SNAP-8 (Acetyl Octapeptide-3)
SNAP-8 is the trade name for Acetyl Octapeptide-3 (also listed as Acetyl Glutamyl Heptapeptide-1), a synthetic eight-residue peptide with the acetylated, C-terminally amidated sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Ac-EEMQRRAD-NH2). It is an elongated analog of the hexapeptide Argireline (Acetyl Hexapeptide-8, Ac-EEMQRR-NH2), extending that sequence by two residues (Ala-Asp); both are described as derived from the N-terminal region of the SNARE protein SNAP-25 and were developed as cosmetic ingredients (Lipotec, now part of Lubrizol Life Science).
The mechanism proposed for this peptide family is competition with SNAP-25 for a position in the SNARE complex, reducing calcium-dependent vesicle fusion. That mechanism was characterized experimentally for the parent hexapeptide Argireline rather than for SNAP-8 itself; for SNAP-8 it is inferred by structural analogy and is asserted mainly by the manufacturer. The independent peer-reviewed literature on SNAP-8 specifically is very thin — a PubMed search returns essentially an analytical-methods paper (an LC-MS/MS assay; Kim et al., 2020) and multi-ingredient formulation studies in which SNAP-8’s individual contribution cannot be isolated. SNAP-8 is not an approved drug and is supplied for laboratory research use only, not for human or veterinary use.
Frequently Asked Questions
What is SNAP-8?
SNAP-8 is a synthetic acetylated octapeptide, INCI name Acetyl Octapeptide-3. Its sequence is Ac-EEMQRRAD-NH2, an elongated version of the hexapeptide Argireline. It is supplied here for laboratory research use only and is not for human or veterinary use.
What is SNAP-8 peptide (Acetyl Octapeptide-3)?
It is an eight-amino-acid synthetic peptide (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2; CAS 868844-74-0), an extended analog of Argireline derived from the SNAP-25 protein sequence. It is a research chemical, not a drug.
What is the difference between SNAP-8 and Argireline?
Argireline is the hexapeptide Acetyl Hexapeptide-8 (Ac-EEMQRR-NH2); SNAP-8 is Acetyl Octapeptide-3, the same six N-terminal residues extended by two more (Ala-Asp) to Ac-EEMQRRAD-NH2. Both are described as derived from the N-terminus of the SNARE protein SNAP-25 and share the same proposed mechanism, which was studied primarily on Argireline. Both are supplied for research use only.
What is the proposed mechanism of SNAP-8?
The proposed mechanism is competition with the protein SNAP-25 within the SNARE complex, reducing calcium-dependent vesicle fusion. It was characterized for the parent peptide Argireline and is inferred for SNAP-8 by structural analogy; it has not been independently demonstrated for SNAP-8 itself. Provided for laboratory research use only.
Is SNAP-8 an approved drug?
No. SNAP-8 is not an approved drug, and the independent peer-reviewed literature on it is limited to an analytical-methods paper and multi-ingredient formulation studies in which its individual contribution cannot be isolated. The material here is supplied strictly for laboratory research use and is not for human use.
Research & References
Independent databases and peer-reviewed literature for SNAP-8. Provided for research reference only.
External resources are independent and not affiliated with or endorsed by PHIOGEN. Listed for laboratory research reference only.
